LOOK OUT FENTANYL! NEW BAD NARCOTIC ARRIVAL IN OUR STATE:
CYCHLORPHINE: NEW SYNTHETIC SUPER OPIATE DRUG DISCOVERY PROMPTS KENTUCKY OFFICIALS TO ISSUE WARNING
FEBRUARY 23, 2026 – written by WADE QUEEN
Kentucky law enforcement have issued a public safety advisory after a new drug that has been detected in Kentucky for the first time, so potemt that Narcan like will not work on the overdose intake ofthe drug.
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The Kentucky Office of Homeland Security warns that Cychlorphine, a highly potent synthetic drug approximately ten times stronger than fentanyl, has been detected in central Kentucky and is contributing to overdose deaths in neighboring regions, including eastern Tennessee.
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This substance is frequently mixed with other illegal narcotics, placing users at extreme risk of unintentional exposure. Its presence is expected to expand to additional areas within the Commonwealth.
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Advisory for First Responders, Healthcare Providers, and Law Enforcement Personnel:
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* Exercise extreme caution when handling any unknown or illicit substances.
* Utilize appropriate personal protective equipment (PPE) to prevent accidental exposure.
* Treat all suspected Cychlorphine-related overdoses as medical emergencies.
* Immediately report any confirmed or suspected cases to local public safety authorities.
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The Kentucky Office of Homeland Security urges the public to remain vigilant, avoid contact with unknown substances, and report suspicious activity to law enforcement.
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ABOUT CYCHLORPHINE:
Cychlorphine (N-Propionitrile chlorphine) is a synthetic opioid chemical compound which has been sold as a designer drug, reported in five European countries since 2024, and in the USA. It has been found in Canada as of September 2025. It is similar in chemical structure to known opioid agonists such as brorphine and spirochlorphine, and is claimed to be an opioid with similar or slightly higher potency than fentanyl, but no pharmacological data for cychlorphine has been published. It is not a structural analog of morphine, despite the similar name. Instead, it is an orphine.
At least 5 people have died from a cychlorphine overdose in England in 2025. Furthermore, it has been detected as the sole active opioid in fake pharmaceutical opioid preparations that are supposed to contain hydromorphone or oxycodone, further increasing the risk of accidental overdoses.
It was added to the German NpSG in December 2025.
